What would be the proper way to restrict users from Storing Data in Local Drive, Desktop, Document, Downloads Etc.
I want to deploy this policy on Hostname basis and not for specific user because that will restrict the same user to access Storage on his other systems where he logins.
What could be the possible solution? Please suggest!
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Create a Group policy object and configure following setting on that to block disk C: User Configuration \ Administrative Templates \ Windows Components \ Windows Explorer. Then on the right side under Setting, double click on Prevent access to drives from My Computer. Then, Select Enable then under Options from the drop down menu you can restrict a certain disk. 
Then you can link that GPO into the OU where your PCs are located. To restrict desktop, You can do like following,
